Irene Pichler

This study shows that increasing SLP-2 levels reduces alpha-synuclein-induced mitochondrial damage and neurodegeneration in Parkinson's disease models.

This study identifies STL-1/SLP-2 as a sensor of oxidative stress that activates the mitochondrial unfolded protein response through interaction with phosphatidic acid.

This study shows dopamine affects iron homeostasis and mitochondrial function in healthy cells and can restore these processes in Parkinson's disease neurons.

The paper identifies mitochondrial DNA heteroplasmy as a marker distinguishing disease manifestation in PINK1/PRKN mutation carriers.