Human labor pain is influenced by the voltage-gated potassium channel KV6.4 subunit
Michael Lee, Michael S. Nahorski, James R.F. Hockley, Van B. Lu, Gillian Ison, Luke A. Pattison, Gerard Callejo, Kaitlin M. Stouffer, Emily V. Fletcher, Christopher Andrew Brown, Ichrak Drissi, Daniel Wren Wheeler, Patrik Ernfors, David Krishna Menon, Frank M. Reimann, , Christopher Geoffrey Woods
The paper identifies a genetic variant in KCNG4 associated with increased labor pain by altering KV6.4 function in uterine nociceptors.
bioRxiv · Feb 19, 2020 · PreprintNeuroscience