Author

Cristina Florea

University of Eastern FinlandORCID 0000-0001-7719-2600Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Alan Jay GrodzinskyiD· 3 shared Atte S. A. EskelineniD· 3 shared Joonas P. KosoneniD· 3 shared Moustafa HamadaiD· 3 shared Petri TanskaiD· 3 shared Rami Kristian KorhoneniD· 3 shared Amir EsrafilianiD· 1 shared Sanna Hakonen· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 27 mutual co-author links

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3 shared papersBiophysics

Alan Jay GrodzinskyORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 2, 2026

A computational framework to model cartilage degeneration induced by mechanoinflammation and cytokine-driven inflammation in post-traumatic osteoarthritis

Moustafa Hamada, Atte S. A. Eskelinen, Joonas P. Kosonen…·Petri Tanska

DOI 10.64898/2026.05.29.728618

mechanistic / dynamical modelsynaptic & neural circuits

𝕏 PostBluesky

BiophysicsPLoS Computational BiologyPeer-reviewedJan 20, 2026

MMP release following cartilage injury leads to collagen loss in intact tissue - a computational study

Moustafa Hamada, Atte S. A. Eskelinen, Joonas P. Kosonen…·Rami Kristian Korhonen

This study develops a computational model to simulate collagen loss in cartilage after injury, showing that MMP release from damaged cells leads to significant collagen degradation.

2 citationstop 3%

statistical modelcell type annotation

𝕏 PostBluesky

BioengineeringPLoS Computational BiologyPeer-reviewedOct 31, 2025

Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content

Atte S. A. Eskelinen, Joonas P. Kosonen, Moustafa Hamada…·Rami Kristian Korhonen

The paper develops a computational model to estimate how mechanoinflammatory mechanisms affect cartilage aggrecan content over time following joint injury.

5 citations

mechanistic / dynamical modelchromatin & epigenetic regulation

𝕏 PostBluesky