Joonas P. Kosonen

This study develops a computational model to simulate collagen loss in cartilage after injury, showing that MMP release from damaged cells leads to significant collagen degradation.

The paper develops a computational model to estimate how mechanoinflammatory mechanisms affect cartilage aggrecan content over time following joint injury.

This paper develops a computational model to simulate impact-induced cartilage damage, oxidative stress, and NAC treatment effects, showing NAC reduces proteoglycan loss by mitigating cell death and enzymatic depletion.