Molecular BiologybioRxivPreprint
Supression of Perforin-like Protein pores inhibit Plasmodium multistage-growth, transmission and erythrocyte senescence
Swati Garg, Abhishek Shivappagowdar, Rahul Singh Hada…·Shailja Singh
This paper identifies PMD as a conserved region of Plasmodium perforin-like proteins that forms pores in erythrocytes, leading to anemia, and shows that anti-PMD inhibitors block parasite growth and transmission across multiple stages.
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