Susan J. Fisher

The paper uses single-nucleus RNA-seq and spatial transcriptomics to show how the maternal-fetal interface diverges in structure and function between the basal plate and chorionic membranes, identifying NID2 as an ancestry-associated regulator of trophoblast invasion.

This study creates a comprehensive single-cell atlas of the maternal-fetal interface, identifying cell-type-specific dysregulation in pregnancy complications.

The paper uses single-cell RNA sequencing to identify a novel cytotrophoblast population in the smooth chorion of the human placenta that functions as a barrier and restricts EVT invasion.

The paper compares small RNA composition across 12 human biofluids, finding large variations in miRNA and tDR levels and identifying Y RNA fragments in several biofluids.