Author

David Allen Dean

University of Rochester MedicineORCID 0000-0001-7748-8073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Emily G. Sorensen· 1 shared J. Gabell· 1 shared Jennasea B. Licata· 1 shared John D. LueckiD· 1 shared Joseph J. PorteriD· 1 shared Julia Hyatt· 1 shared Kari ThrasheriD· 1 shared Luke K Peterson· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Emily G. Sorensen

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1 paper

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 23, 2026

Anticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors

Joseph J. Porter, Wooree Ko, Emily G. Sorensen…·John D. Lueck

This paper demonstrates that DNA-based ACE-tRNA minivectors effectively suppress nonsense mutations in CFTR and REP1, with improved bioavailability and stability compared to plasmid DNA vectors.

5 citationstop 2%

humanDNA methylation

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