Author

Emily G. Sorensen

University of Rochester Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

John D. LueckiD· 2 shared Joseph J. PorteriD· 2 shared Wooree KoiD· 2 shared David Allen DeaniD· 1 shared J. Gabell· 1 shared Jennasea B. Licata· 1 shared Julia Hyatt· 1 shared Kari ThrasheriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

John D. LueckORCID

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 23, 2026

Anticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors

Joseph J. Porter, Wooree Ko, Emily G. Sorensen…·John D. Lueck

This paper demonstrates that DNA-based ACE-tRNA minivectors effectively suppress nonsense mutations in CFTR and REP1, with improved bioavailability and stability compared to plasmid DNA vectors.

5 citationstop 2%

humanDNA methylation

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Molecular BiologyNucleic Acids ResearchPeer-reviewedOct 28, 2024

Optimization of Anticodon Edited Transfer RNAs (ACE-tRNAs) Function in Translation for Suppression of Nonsense Mutations

Joseph J. Porter, Wooree Ko, Emily G. Sorensen, John D. Lueck

This study optimizes ACE-tRNA function to suppress nonsense mutations, reducing the required amount by ~16-fold for common cystic fibrosis-causing PTCs.

26 citations

experimental assay

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