Author

Louise Vagner Laursen

Uppsala UniversityORCID 0000-0001-7758-4487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1 Approach:statistical model· 1

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Jelena ČalyševaiD· 1 shared Per JemthiD· 1 shared Toby J. GibsoniD· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperMolecular Biology

Jelena ČalyševaORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular Biology and EvolutionPeer-reviewedAug 1, 2020

Divergent evolution of a protein-protein interaction revealed through ancestral sequence reconstruction and resurrection

Louise Vagner Laursen, Jelena Čalyševa, Toby J. Gibson, Per Jemth

The paper reconstructs and resurrects ancestral sequences of PDZ3 and CRIPT to study the evolutionary dynamics of their interaction, finding it ancient but with reduced affinity in nematodes and insects.

8 citations

humanmouse

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