Author

Jelena Čalyševa

Heidelberg UniversityORCID 0000-0003-1047-4157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Louise Vagner LaurseniD· 1 shared Per JemthiD· 1 shared Toby J. GibsoniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperMolecular Biology

Louise Vagner LaursenORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular Biology and EvolutionPeer-reviewedAug 1, 2020

Divergent evolution of a protein-protein interaction revealed through ancestral sequence reconstruction and resurrection

Louise Vagner Laursen, Jelena Čalyševa, Toby J. Gibson, Per Jemth

The paper reconstructs and resurrects ancestral sequences of PDZ3 and CRIPT to study the evolutionary dynamics of their interaction, finding it ancient but with reduced affinity in nematodes and insects.

8 citations

humanmouse

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