Roger P. Wise

This study shows that powdery mildew fungi inhibit the vacuolar trafficking pathway to suppress NLR-mediated immunity in barley, but this inhibition is temporary and can be reversed by later-secreted effectors.

The paper identifies effector-host protein interactions in barley powdery mildew, revealing key targets involved in ubiquitin processes and transcriptional regulation.

The paper sequenced wild barley to identify genetic markers linked to agronomic traits and found novel loci for stem rust resistance and days to heading.

The paper analyzes transcriptome data from barley infected with powdery mildew to study host-pathogen interactions, identifying gene effects and co-expression patterns in the pathogen.

The paper constructs a barley interactome using interolog inference and integrates it with omics data to model immune signaling and identify novel MLA interactors.

FINDER automatically annotates eukaryotic genes from RNA-Seq data and associated protein sequences, improving accuracy by integrating raw reads and protein evidence.

NGPINT identifies protein-protein interactions using Y2H data, achieving 95% accuracy in simulated tests and recognizing all validated interactions in published datasets.

Y2H-SCORES provides a statistical framework to identify protein-protein interactions from yeast-two-hybrid sequence data by evaluating enrichment, specificity, and in-frame selection.