Thomas Hu

This study develops a 3D bone marrow-on-a-chip model to investigate interactions between CAR-T cells and multiple myeloma cells in different niches and assess therapeutic responses.

The paper introduces SNOWFLAKE, a graph neural network framework that predicts disease status from multiplex imaging data in human B-cell follicles, showing improved performance over other methods.

The paper introduces spaGNN, a method to analyze subcellular spatial gene neighborhoods in MSCs and chondrocytes, revealing tissue-specific transcriptional and spatial features.