Author

Matei Teleman

SIB Swiss Institute of BioinformaticsORCID 0000-0001-7834-3992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

David GfelleriD· 3 shared Aurélie AG GabrieliD· 2 shared Léonard HéraultiD· 2 shared Alexandra Michel· 1 shared Alexandre HarariiD· 1 shared Amédé Larabi· 1 shared Anne‐Christine Thierry· 1 shared Dana Léa MorenoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioinformatics

David GfellerORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 17, 2025

Key determinants of T cell epitope recognition revealed by TCR specificity profiles

Yan Liu, Giancarlo Croce, Daniel M. Tadros…·David Gfeller

The paper introduces TCR specificity profiles to identify key determinants of TCR-epitope recognition and shows their ability to predict cross-reactivity and interpret machine learning models.

4 citations

proteomicsdeep learning

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedDec 6, 2024

SuperSpot: Coarse Graining Spatial Transcriptomic Data into Metaspots

Matei Teleman, Aurélie AG Gabriel, Léonard Hérault, David Gfeller

SuperSpot reduces spatial transcriptomic data size and noise by grouping similar spots into metaspots using graph-based clustering.

2 citations

spatial transcriptomicsstatistical model

𝕏 PostBluesky

BioinformaticsMolecular Systems BiologyPeer-reviewedMay 29, 2024

Building and analyzing metacells in single-cell genomics data

Mariia Bilous, Léonard Hérault, Aurélie AG Gabriel…·David Gfeller

The paper reviews metacell applications in single-cell genomics, provides a tutorial, and introduces a pipeline for metacell construction and analysis.

18 citations

scRNA-seqstatistical model

𝕏 PostBluesky