SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment
Wenda Zhang, Lili Lin, Haoxuan Ying, Nan Li, Xinyi Zhou, Qi Yang, Shulu Hu, Jiayi Cai, Anqi Lin, Cheng Quan, Zaoqu Liu, Jian Zhang, Peng Luo, Ting Wei
This study identifies SPP1+ tumor-associated macrophages as a key driver of radioresistance in nasopharyngeal carcinoma through interactions with the tumor microenvironment.
bioRxiv · Oct 23, 2024 · PreprintCancer Biology