Author

Ting Wei

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:diffusion model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Zhuoqi ZhengiD· 4 shared Junjie ZhuiD· 3 shared Xiaokun HongiD· 3 shared Haifeng CheniD· 2 shared Bo ZhangiD· 1 shared Bo ZhangiD· 1 shared Bozitao ZhongiD· 1 shared Cheng LiuiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersBioinformatics

Zhuoqi ZhengORCID

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4 papers

Recent·Most cited

DynaRNA: Dynamic RNA Conformation Ensemble Generation with Diffusion Model

Zhengxin Li, Junjie Zhu, Xiaokun Hong, Zhuoqi Zheng, Taeyoung Cui, Yutong Sun, Ting Wei, Haifeng Chen

DynaRNA generates RNA conformation ensembles using a diffusion model with EGNN, outperforming MD simulations in accuracy and efficiency.

bioRxiv · May 22, 2025 · PreprintBioinformatics

AI-Driven Efficient De Novo design of GLP-1RAs with Extended Half-Life and Enhanced Efficacy

Ting Wei, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Taiying Cui, Cheng Liu, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Zhangsheng Yu, Haifeng Chen

This paper designs 10,000 de novo GLP-1RAs using AI, with 60 passing stability, efficacy, and diversity criteria, and two showing extended half-lives and superior efficacy in vivo.

bioRxiv · Mar 26, 2025 · PreprintBioengineering

Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion Models

Junjie Zhu, Zhengxin Li, Bo Zhang, Zhuoqi Zheng, Bozitao Zhong, Jie Bai, Xiaokun Hong, Taifeng Wang, Ting Wei, Jianyi Yang, Haifeng Chen

This paper introduces IDPFold, a diffusion model that generates conformational ensembles for intrinsically disordered proteins directly from sequences, without requiring MSA or experimental data.

bioRxiv · May 5, 2024 · PreprintBioinformatics

Protein Language Model Supervised Scalable Approach for Diverse and Designable Protein Motif-Scaffolding with GPDL

Bo Zhang, Kexin Liu, Zhuoqi Zheng, Yunfeiyang Liu, Junxi Mu, Ting Wei, Haifeng Chen

The paper introduces GPDL, a protein language model approach for motif-scaffolding that outperforms existing methods in generating diverse and accurate protein structures.

bioRxiv · Oct 26, 2023 · PreprintBioinformatics