Stephen J. O’Brien

This study identifies rare genetic variants associated with HIV-1 progression in a Botswana population using whole genome sequencing and statistical analysis.

The paper characterizes human genomic variations and mutation burden in Botswana using whole genome sequencing, identifying damaging variants and admixture patterns.

The paper analyzes whole-genome sequences of Mycobacterium tuberculosis isolates from pulmonary and extrapulmonary tuberculosis patients in Russia to identify genetic substrains and drug resistance patterns.

The paper develops a genome assembly strategy for the critically endangered Solenodon paradoxus, revealing population history and genetic features.