Author

Andrea Piserchio

City College of New YorkORCID 0000-0001-7865-9065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Kevin N. DalbyiD· 2 shared Kimberly J. LongiD· 2 shared Luke Samuel BrowningiD· 2 shared Ranajeet GhoseiD· 2 shared Amanda L. BohanoniD· 1 shared Clint D.J. Tavares· 1 shared Elizabeth Y WangiD· 1 shared Eta A. IsiorhoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Kevin N. DalbyORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedDec 22, 2025

Ser500 phosphorylation acts as a conformational switch to prime eEF-2K for activation

Amanda L. Bohanon, Luke Samuel Browning, Andrea Piserchio…·Kevin N. Dalby

This study shows that S500 phosphorylation primes eEF-2K for activation by enhancing its intrinsic activity and facilitating CaM-dependent activation.

1 citation

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiochemistryJournal of Biological ChemistryPeer-reviewedAug 28, 2025

The Critical Role of the C-terminal Lobe of Calmodulin in Activating Eukaryotic Elongation Factor 2 Kinase

Kimberly J. Long, Luke Samuel Browning, Andrea Piserchio…·Kevin N. Dalby

This study shows that the C-terminal lobe of calmodulin can fully activate eEF-2K independently of Ca2+ and external CaM, revealing a unique activation mechanism.

2 citations

experimental assay

𝕏 PostBluesky