Author

Ranajeet Ghose

The Graduate Center, CUNYORCID 0000-0002-0763-8686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Andrea PiserchioiD· 2 shared Kevin N. DalbyiD· 2 shared Kimberly J. LongiD· 2 shared Luke Samuel BrowningiD· 2 shared Amanda L. BohanoniD· 1 shared Clint D.J. Tavares· 1 shared Elizabeth Y WangiD· 1 shared Eta A. IsiorhoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Andrea PiserchioORCID

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2 papers

Recent·Most cited

Ser500 phosphorylation acts as a conformational switch to prime eEF-2K for activation

Amanda L. Bohanon, Luke Samuel Browning, Andrea Piserchio, Kimberly J. Long, Sharon Jacob, Rae M. Sammons, Clint D.J. Tavares, Eun Jeong Cho, Ranajeet Ghose, Kevin N. Dalby

This study shows that S500 phosphorylation primes eEF-2K for activation by enhancing its intrinsic activity and facilitating CaM-dependent activation.

Journal of Biological Chemistry · Dec 22, 2025Peer-reviewedBiochemistry

The Critical Role of the C-terminal Lobe of Calmodulin in Activating Eukaryotic Elongation Factor 2 Kinase

Kimberly J. Long, Luke Samuel Browning, Andrea Piserchio, Eta A. Isiorho, Mohamed I. Gadallah, Jomai Douangvilay, Elizabeth Y Wang, Justin K. Kalugin, Jennifer S. Brodbelt, Ranajeet Ghose, Kevin N. Dalby

This study shows that the C-terminal lobe of calmodulin can fully activate eEF-2K independently of Ca2+ and external CaM, revealing a unique activation mechanism.

Journal of Biological Chemistry · Aug 28, 2025Peer-reviewedBiochemistry