Systems BiologybioRxivPreprint
SpY-C: Supervised Learning of Phosphopeptide Sequence Constraints Enables Global Prediction of SH2 Domain Binding
Alekhya Abhiram Kandoor, Anny Carolline Silva Oliveira, Kazuya Machida…·Kristen M. Naegle
SpY-C classifies phosphopeptide sites as potential SH2 domain binders using supervised learning, improving annotation of pY function and informing downstream machine learning approaches.
DOI 10.64898/2026.08.18.744962