Author

Marion MacFarlane

University of CambridgeORCID 0000-0001-7886-1159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea BrancaleiD· 1 shared Andreia M. Ribeiro da Silva· 1 shared Andrew CraxtoniD· 1 shared Andrew D. WestwelliD· 1 shared Angela RubioiD· 1 shared Anne E. WillisiD· 1 shared Athina Varnava· 1 shared Catarina de Matos Ferraz FrancoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Andrea BrancaleORCID

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2 papers

Recent·Most cited

Molecular BiologyCell Death and DiseasePeer-reviewedOct 30, 2026

YBX3 overexpression in mesothelioma drives aberrant cell proliferation

Angela Rubio, Robert F. Harvey, Andrew Craxton…·Anne E. Willis

This study identifies YBX3 as an oncoprotein in mesothelioma that drives cell proliferation through SLC7A5/LAT1-mediated amino acid uptake and shows JPH203 as a potential therapeutic agent.

DOI 10.1038/s41419-026-09389-3

humanbulk RNA-seq

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Cancer BiologyAcademia oncology.Peer-reviewedApr 29, 2025

The Discovery of Small Molecule Inhibitors of cFLIP that Sensitise Tumour Cells to TRAIL

Gilda Giancotti, Rhiannon French, Olivia A. Hayward…·Andrea Brancale

This paper identifies small molecule inhibitors of cFLIP that enhance TRAIL-induced apoptosis in breast cancer cells and improves their potency through structure-activity relationship studies.

2 citations

humanproteomics

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