Lothar C. Dieterich

This study quantitatively characterizes the lipid composition of extracellular vesicles from multiple cell lines to identify biomarkers and inform EV engineering.

The paper identifies plasmacytoid dendritic cells (pDCs) in tumor-draining lymph nodes as a potential biomarker for predicting response to PD-L1 blockade therapy in melanoma.

The paper identifies widespread transcription initiation at microsatellites across species and develops deep learning models to predict STR-associated transcription and its impact on disease variants.