Loss of cardiomyocyte eukaryotic elongation factor 1A2 in mice triggers cardiomyopathy due to defective proteostasis
Abel Martín-Garrido, Nadine Weyrauch, Jorge Ruiz‐Orera…·Joerg Heineke
This study shows that loss of eEF1A2 in cardiomyocytes causes cardiomyopathy through proteostasis defects, and mTORC1 inhibition can reverse the condition.