Developmental BiologybioRxivPreprint
The DNA damage response regulates the oocyte pool in mammals
Ana Martínez-Marchal, Maria Teresa Guillot, Mònica Ferrer‐Roda…·Ignasi Roig
This study shows that the DNA damage response, specifically CHK2, regulates oocyte elimination and follicle formation in mammals by controlling meiotic recombination and cyst breakdown.
DOI 10.1101/816488