Ignasi Roig

This study shows that SIRT7 maintains genome stability in aging mouse testes by regulating H3K36ac, preventing premature loss of spermatogonia and meiotic defects.

This study shows TRIP13 is involved in transcription suppression and DSB repair during meiosis, with distinct roles in spermatocytes and oocytes.

This study shows that full-length BEND2 is not needed for male fertility but is essential for establishing the ovarian reserve in mice.

This study characterizes the dynamics of primary cilia in prepubertal mouse spermatocytes, revealing their emergence after the first meiotic wave and potential roles in DNA repair and spermatogenesis.

This study shows that the DNA damage response, specifically CHK2, regulates oocyte elimination and follicle formation in mammals by controlling meiotic recombination and cyst breakdown.

This study shows that the mouse SWS1-SWSAP1 complex is essential for meiotic recombination by promoting RAD51 and DMC1 focus formation, with BRCA2 C terminus playing a modulatory role.