Author

Joshua A. Chu‐Tan

Australian National UniversityORCID 0000-0001-7936-8972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Riccardo NatoliiD· 3 shared Adrian V. CioancaiD· 2 shared Riemke Aggio‐BruceiD· 2 shared Ulrike SchümanniD· 2 shared Yvette WooffiD· 2 shared Andrew FeolaiD· 1 shared Gabriela Sanchez Rodriguez· 1 shared Hardip R. PateliD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Riccardo NatoliORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 16, 2025

Forced exercise modulates retinal inflammatory response and regulates miRNA expression to promote retinal neuroprotection during degeneration

Hayden Haupt, Vivian S. Chen, Teele Palumaa…·Katie L. Bales

This study shows treadmill exercise reduces inflammation and alters miRNA expression in a light-induced retinal degeneration model, preserving retinal function and photoreceptor density.

DOI 10.1101/2025.07.16.665187

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologyMolecular NeurodegenerationPeer-reviewedAug 31, 2021

Functional microRNA targetome undergoes degeneration-induced shift in the retina

Joshua A. Chu‐Tan, Zhi-Ping Feng, Yvette Wooff…·Riccardo Natoli

The paper identifies a shift in the active miRNA targetome in a mouse model of retinal degeneration, showing changes in miRNA binding regions and AGO2 localization.

19 citations

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologyFrontiers in Cellular NeurosciencePeer-reviewedJun 25, 2020

Extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene therapy.

Yvette Wooff, Adrian V. Cioanca, Joshua A. Chu‐Tan…·Riccardo Natoli

This study investigates the role of retinal extracellular vesicles and their miRNA cargo in retinal health and degeneration, showing their involvement in immune modulation and potential for gene therapy.

68 citationstop 5%

mousebulk RNA-seq

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