Jill A. Hollenbach

The paper analyzes HLA variation across six ancestry groups in the All of Us Research Program to identify HLA-phenotype associations and assess ancestry-specific genetic architecture.

This study analyzes KIR diversity in HIV-infected children from Uganda and Botswana, finding differences in allele frequencies and associations with disease progression.

This study identifies distinct autoreactomes in healthy individuals based on HLA-DRB1 genotype using PhIP-Seq, showing genotype-specific autoantibody profiles and potential pathogenic autoantibodies before disease onset.

This study identifies 15 novel HLA associations with underreported conditions using high-resolution HLA genotypes and self-reported health data from 70,724 individuals.

Paired CSF and blood scRNA/TCR-seq in treatment-naive MS shows a small set of expanded, cytotoxic CSF-enriched CD8+ clonotypes, two of which recognize EBV epitopes.

MHConstructor provides a haplotype-informed, high-throughput pipeline for de novo MHC assembly from short read data, improving upon reference-based methods.

The paper develops C4Investigator, a bioinformatic pipeline for high-throughput analysis of C4 gene variants from genomic data, revealing high poly-allelic variation in the 1000 Genomes Project Dataset.

This study examines the association between HLA genotype and SARS-CoV-2 disease severity in 3,235 individuals, finding limited impact compared to demographic and clinical factors.

The paper examines how self-reported race and geographic ancestry relate to genetic data in a large U.S. cohort, finding that combining both measures better reflects genetic ancestry than either alone.