Hubert Tsui

This study identifies MBD1-L, an aberrantly spliced transcript in MDS, which drives epigenetic changes leading to myeloerythroid defects, and shows ASO-based targeting can restore erythroid differentiation.

ClumPyCells corrects cell size biases in spatial -omics data to accurately measure cell and marker aggregation in tissues.

This paper introduces PGDIPS, a physics-guided deep learning method for stain deconvolution in histopathology images, achieving better generalization and interpretability without training data.