Author

Daisuke Hatta

Nagasaki UniversityORCID 0000-0001-7972-1852Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Kaori WatanabeiD· 1 shared Keiro ShirotaniiD· 1 shared Nobuhisa IwataiD· 1 shared Takaomi C. SaidoiD· 1 shared Takashi SaitoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Kaori WatanabeORCID

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1 paper

Recent·Most cited

NeuroscienceExperimental NeurologyPeer-reviewedJun 24, 2026

Trem2 R47H mutation shows mild, but functionally divergent alterations in microglial phenotypes compared to Trem2 deficiency in aged AppNL-F knock-in mice

Keiro Shirotani, Daisuke Hatta, Kaori Watanabe…·Nobuhisa Iwata

This study compares the effects of TREM2 R47H mutation and TREM2 deficiency in aged AppNL-F mice, finding that the mutation causes mild, functionally distinct microglial changes compared to a null effect.

DOI 10.1016/j.expneurol.2026.115894

mousestatistical model

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