Author

Luca Johannes Schlotheuber

ETH ZurichORCID 0000-0001-8024-1581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:contrastive learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:optimal transport· 1 Assay:proteomics· 1

Frequent Co-Authors

Klaus EyeriD· 2 shared Alessandro StreuliiD· 1 shared Aline LinderiD· 1 shared Deborah GreisiD· 1 shared Ines LüchtefeldiD· 1 shared Michael VollenweideriD· 1 shared Richard Danis· 1 shared Simon N. Agersnap· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Klaus EyerORCID

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2 papers

Recent·Most cited

Single-antibody mutational scanning reveals poly-specificity and immune constraints in vaccination responses

Luca Johannes Schlotheuber, Simon N. Agersnap, Deborah Greis, Alessandro Streuli, Yohei Yamauchi, Klaus Eyer

The paper introduces a method to analyze antibody repertoires against a large library of SARS-CoV-2 RBD variants, revealing poly-specificity and immune constraints in vaccination responses.

bioRxiv · Jan 7, 2026 · PreprintImmunology

High-Resolution Time-Lapse Imaging of Droplet-Cell Dynamics via Optimal Transport and Contrastive Learning

Luca Johannes Schlotheuber, Michael Vollenweider, Sven Gutjahr, Tiago Hungerland, Richard Danis, Weronika Ormaniec, Aline Linder, Valentina Boeva, Ines Lüchtefeld, Klaus Eyer

This paper develops a method to track microfluidic droplets over time using optimal transport and contrastive learning, achieving high accuracy in tracking without labeled data.

Lab on a Chip · Jan 1, 2025Peer-reviewedBioinformatics