Yohei Yamauchi

Single-antibody mutational scanning reveals poly-specificity and immune constraints in vaccination responses

The paper introduces a method to analyze antibody repertoires against a large library of SARS-CoV-2 RBD variants, revealing poly-specificity and immune constraints in vaccination responses.

Enhanced Visualization of Influenza A Virus Entry Using Virus-View Atomic Force Microscopy

This study uses ViViD-AFM to visualize influenza A virus entry into cells, revealing nanoscale interactions and endocytosis mechanisms.

ATG16L1 WD domain regulates lipid trafficking to maintain plasma membrane integrity to limit influenza virus infection

Influenza A virus exploits the motility of membrane cytoskeletal actomyosin filaments for its genome packaging in the host cell

This study shows that influenza A virus uses actomyosin motility for vRNP packaging by blocking myosin activity and observing disrupted vRNP aggregation.

Ubiquitination mediates protein localization in RNA virus-infected cells

The paper identifies virus-induced ubiquitination in monocytes, showing it regulates protein localization and inhibits antiviral responses.

Regression plane concept: analysing continuous cellular processes with machine learning

The paper introduces Regression Plane, a tool for continuous phenotypic analysis using machine learning without requiring class labels.