ImmunologybioRxivPreprint
TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells
Hoyoung Lee, Soyoung Kim, Sang-Hoon Kim…·Eui‐Cheol Shin
This study identifies NFATc1 as a suppressor of IL-15-induced NK-like activation in human memory CD8+ T cells via the Ca2+-calcineurin pathway and defines a gene signature associated with bystander activation.
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