GenomicsbioRxivPreprint
An optimised protocol for quality control of gene therapy vectors using Nanopore direct RNA sequencing
Kathleen Zeglinski, Christian Montellese, Matthew E. Ritchie…·Arthur L. Hsu
This paper compares long-read sequencing technologies to identify RNA quality issues in lentiviral vectors, finding Nanopore direct RNA sequencing most effective for detecting incomplete RNA.