This study investigates the distinct roles of prph2a/b and rom1a/b in zebrafish photoreceptor outer-segment assembly, showing prph2a/b are critical for cone OSs while rom1a/b are essential for rod OSs.

DOI 10.64898/2026.08.06.743304

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 26, 2024

Cdhr1a and pcdh15b link photoreceptor outer segments with inner segment calyceal processes revealing a potential mechanism for cone-rod dystrophy.

Meet K. Patel, Warlen Pereira Piedade, Jakub K. Famulski

DOI 10.1101/2024.07.26.605360

zebrafishimaging

𝕏 PostBluesky

Developmental BiologyDifferentiationPeer-reviewedDec 9, 2022

Zebrafish anterior segment mesenchyme progenitors are defined by function of tfap2a but not sox10.

Oliver Vöcking, Kristyn L. Van Der Meulen, Meet K. Patel, Jakub K. Famulski

The paper identifies tfap2a as critical for anterior segment mesenchyme specification in zebrafish, while sox10 is dispensable for this process.

9 citations

zebrafishexperimental assay

𝕏 PostBluesky