Author

Yelena Guttman

University of California, San FranciscoORCID 0000-0001-8108-0900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ahituv NadaviD· 1 shared Beniamin KrupkiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperGenetics

Ahituv NadavORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintApr 24, 2026

Massively parallel reporter assays for CYP3A4 enhancer variants alongside their native promoter

Yelena Guttman, Beniamin Krupkin, Ahituv Nadav

The paper uses a modified MPRA to assess CYP3A4 enhancer variants with their native promoter, identifying variants with significant regulatory impact on drug response and cancer severity.

DOI 10.64898/2026.04.22.719677

humanexperimental assay

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