Author

Breann L. Brown

Vanderbilt UniversityORCID 0000-0001-8109-4472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

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Alexis B. RobersoniD· 1 shared Iva ChitrakariD· 1 shared Pedro H Ayres-GalhardoiD· 1 shared

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2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

Alexis B. RobersonORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedDec 22, 2025

A reversible feedback mechanism regulating mitochondrial heme synthesis

Iva Chitrakar, Alexis B. Roberson, Pedro H Ayres-Galhardo, Breann L. Brown

This study identifies a reversible feedback mechanism where heme inhibits mature mitochondrial ALAS2, regulating heme synthesis and providing insights into its spatial control.

7 citations

humanexperimental assay

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