Author

Xiaoxiao Liu

Case Western Reserve UniversityORCID 0000-0001-8115-8624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 3 Assay:Hi-C· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Fulai JiniD· 3 shared Leina LuiD· 3 shared Jian CuiiD· 2 shared Anthony J. GriswoldiD· 1 shared Aura María RamíreziD· 1 shared Changiz GeulaiD· 1 shared Cynthia F. BartelsiD· 1 shared David BennettiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Fulai JinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJul 16, 2026

Cross-platform Hi-C meta-analysis identifies functional insulators that actively block enhancer-promoter interactions

Jian Cui, Wanying Xu, Xiaodong Lang…·Fulai Jin

The paper identifies functional insulators (FINs) through Hi-C meta-analysis, showing they block enhancer-promoter interactions and are distinct from TAD boundaries.

DOI 10.1038/s41467-026-75801-3

humanHi-C

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 17, 2026

Enhanced Hi-C Capture Analysis reveals complex regulatory architecture at the PICALM-EED locus for Alzheimer Disease

Luciana Bertholim Nasciben, Liyong Wang, Wanying Xu…·Jeffery M. Vance

This study uses eHiCA to identify regulatory interactions at the PICALM-EED locus, showing distinct chromatin interactions for SNPs within a segregating haplotype.

DOI 10.64898/2026.02.14.705927

humanHi-C

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 22, 2019

Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

Leina Lu, Xiaoxiao Liu, Wei‐Kai Huang…·Fulai Jin

The paper develops an improved Hi-C protocol and bias-correction pipeline to map chromatin loops in human neurogenesis and brain tissues, showing their role in neural differentiation and GWAS gene identification.

3 citations

humanHi-C

𝕏 PostBluesky