Author

Mengyuan Kan

Children's Hospital of PhiladelphiaORCID 0000-0001-8132-4776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:optimal transport· 1

Frequent Co-Authors

Amaar MarefiiD· 1 shared Amit Bar‐OriD· 1 shared Amy Tara WaldmaniD· 1 shared Andreas Schulte‐MecklenbeckiD· 1 shared Anna Melamed· 1 shared Ayman RezkiD· 1 shared Brenda BanwelliD· 1 shared Caroline J. DiorioiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amaar MarefiORCID

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2 papers

Recent·Most cited

BioinformaticsGigaSciencePeer-reviewedJan 1, 2026

GROTIA: An Interpretable Graph-Regularized Optimal TransportFramework for Diagonal Single-Cell IntegrativeAnalysis

Zexuan Wang, Qipeng Zhan, Shu Yang…·Li Shen

GROTIA aligns multi-omics single-cell datasets using optimal transport and graph regularization, identifying key biological markers and enabling novel subpopulation discovery.

1 citation

scRNA-seqoptimal transport

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 27, 2025

Pediatric cerebrospinal fluid immune profiling distinguishes pediatric-onset multiple sclerosis from other pediatric-onset acute neurological disorders

Diego A. Espinoza, Tobias Zrzavy, Gautier Bréville…·Amit Bar‐Or

This study identifies immune profiles in pediatric cerebrospinal fluid to differentiate pediatric-onset multiple sclerosis from other inflammatory neurological disorders.

DOI 10.1101/2025.02.27.637541

humanflow cytometry

𝕏 PostBluesky