Author

David M. Barrett

ORCID 0000-0001-8132-6819Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Allison Barz LeahyiD· 1 shared Ash A. AlizadehiD· 1 shared Astraea Jager· 1 shared Bita SahafiD· 1 shared Bonnie YatesiD· 1 shared Brian J. SworderiD· 1 shared Charles Grenfell MullighaniD· 1 shared Crystal Lee MackalliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Allison Barz LeahyORCID

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedApr 23, 2025

IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia

Pablo Domizi, Jolanda Sarno, Astraea Jager…·Kara Lynn Davis

This study identifies IKAROS as a factor associated with antigen escape in B-ALL, showing that low IKAROS levels lead to reduced B-cell antigen expression and resistance to CD19- and CD22-targeted therapies.

22 citationstop 2%

humanbulk RNA-seq

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