Döst Öngür

The paper shows that higher variance in schizophrenia patients arises from greater perturbation counts, not disease-specific factors, highlighting the need to address broad damaging factors rather than specific pathologies.

The paper investigates the link between poor self-reported sleep and prolonged white matter T2 relaxation in patients with psychotic disorders, finding a significant correlation with water T2 relaxation times.

Exomes of 24,248 schizophrenia cases and 97,322 controls implicate ultra-rare damaging variants in 10 genes, including GRIN2A and GRIA3, with odds ratios of 3 to 50.

The paper examines stress-induced changes in mPFC glutamate using MRS in humans and finds disrupted glutamatergic adaptation in MDD associated with pessimistic beliefs.

The paper examines functional connectomes across psychiatric diagnoses, finding common disruptions in network function across different pathologies and severity scaling, while psychotic symptoms show distinct disruptions.

The paper identifies distinct functional recovery trajectories in first episode psychosis patients using data-driven methods and explores associated risk factors.

The paper identifies network disruptions in brain regions associated with mania in both lesion-induced mania and bipolar disorder.