The paper examines associations between mPFC glutamatergic metabolites, redox balance, childhood maltreatment, and perceived stress in women with and without MDD.

bioRxiv · Oct 30, 2026 · PreprintNeuroscience

Poor Self-Reported Sleep is Associated with Prolonged White Matter T2 Relaxation in Psychotic Disorders

Ümit Haluk Yeşilkaya, Xi Chen, Lauren Watford, Emma McCoy, Ilgin Genc, Fei Du, Döst Öngür, Çağrı Yüksel

The paper investigates the link between poor self-reported sleep and prolonged white matter T2 relaxation in patients with psychotic disorders, finding a significant correlation with water T2 relaxation times.

bioRxiv · Jul 3, 2024 · PreprintNeuroscience

Glutamatergic adaptation to stress in medial prefrontal cortex underlies risk and resilience for pessimistic beliefs

Jessica A. Cooper, Makiah R. Nuutinen, Victoria M. Lawlor, Brittany A. M. DeVries, Elyssa M Barrick, Shabnam Hossein, Daniel C. Cole, Chelsea V. Leonard, Andrew P. Teer, Grant S. Shields, George M. Slavich, Döst Öngür, John Eric Jensen, Fei Du, Diego A. Pizzagalli, Michael Tilghman Treadway

The paper examines stress-induced changes in mPFC glutamate using MRS in humans and finds disrupted glutamatergic adaptation in MDD associated with pessimistic beliefs.

bioRxiv · Jun 3, 2020 · PreprintNeuroscience

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Lihong Zhan, Grietje Krabbe, Fei Du, Ian Richard Jones, Meredith C. Reichert, Maria A. Telpoukhovskaia, Lay Kodama, Chao Wang, Seo-Hyun Cho, Faten A. Sayed, Yaqiao Li, David Le, Yungui Zhou, Yin Shen, Brian L. West, Li Gan

This study shows that adult microglia self-renew to restore homeostasis after ablation, with specific maturation programs and spatial organization.

PLoS Biology · Feb 8, 2019Peer-reviewedNeuroscience