Mihir Bafna

Promera is a generative model for biomolecular structure prediction, filtering, and design that improves binder filtering and controllable design compared to existing methods.

This paper introduces a computational method to predict higher-order genetic interactions, demonstrating its effectiveness in yeast by predicting trigenic interactions and uncovering biological functions related to cell growth.

This paper introduces ProDiT, a multimodal diffusion model for generating functional proteins with multiple states, demonstrating its ability to design proteins with specific molecular functions and allosteric regulation.