Author

Peyman Petramfar

Thomas Jefferson UniversityORCID 0000-0001-8191-4637Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Matthew D. ByrneiD· 1 shared Richard Jay SmeyneiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperNeuroscience

Matthew D. ByrneORCID

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NeurosciencebioRxivPreprintJul 29, 2024

Templating of Monomeric Alpha-Synuclein Induces Inflammation and SNpc Dopamine Neuron Death in a Genetic Mouse Model of Synucleinopathy.

Matthew D. Byrne, Peyman Petramfar, Richard Jay Smeyne

This study shows that monomeric alpha-synuclein induces inflammation and dopamine neuron death in A53T SNCA mice, suggesting a mechanism for PD in humans with SNCA mutations.

1 citation

mouseexperimental assay

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