Animal Behavior & CognitionScience Translational MedicinePeer-reviewed
Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of HNRNPH2-related neurodevelopmental disorder
Ané Korff, Xiaojing Yang, Ozan Ozdemir…·J. Paul Taylor
This study tests antisense oligonucleotides targeting Hnrnph2 in a mouse model, showing reduced Hnrnph2 levels, increased Hnrnph1, and improved phenotypes like seizures and motor function.
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