BiochemistrybioRxivPreprint
A free energy landscape screen reveals the disordered conformational ensemble of tropoelastin
Sean E. Reichheld, Lisa D. Muiznieks, Zi Hao Liu…·Simon J. Sharpe
The paper introduces FELS, a method to screen free energy landscapes for disordered proteins, and applies it to tropoelastin, revealing its conformational ensemble and resolving conflicting models.
DOI 10.64898/2026.02.03.703507