Aberrant regulation of the Rap1 small GTPase in response to escalating, intermittent stress produces hippocampal synaptic and cognitive dysfunction
Kathryn J. Bjornson, Amanda M. Vanderplow, Yezi Yang, Bailey A. Kermath, Michael E. Cahill
This study shows that increased Rap1 in the hippocampal CA3 region due to stress causes dendritic spine and cognitive dysfunction.
bioRxiv · Jul 3, 2023 · PreprintNeuroscience