Author

Chiara Pirazzini

Istituto delle Scienze Neurologiche di BolognaORCID 0000-0001-8248-0295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:DNA methylation· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Francesco RavaioliiD· 3 shared Maria Giulia BacaliniiD· 3 shared Paolo GaragnaniiD· 3 shared Alena KalyakulinaiD· 2 shared Claudio FranceschiiD· 2 shared Igor YusipoviD· 2 shared Mikhail IvanchenkoiD· 2 shared Alessandro SilvaniiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMolecular Biology

Francesco RavaioliORCID

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3 papers

Recent·Most cited

Molecular BiologyFrontiers in Aging NeurosciencePeer-reviewedMay 21, 2024

Increased hippocampal epigenetic age in the Ts65Dn Mouse Model of Down Syndrome

Francesco Ravaioli, Fiorenza Stagni, Sandra Guidi…·Maria Giulia Bacalini

The paper measures epigenetic age in Ts65Dn mice using a mouse-specific clock and finds increased hippocampal epigenetic age compared to controls, with DNA methylation changes similar to those in humans with Down syndrome.

3 citations

mouseDNA methylation

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Genetic & Genomic MedicineFrontiers in Aging NeurosciencePeer-reviewedMar 11, 2021

A meta-analysis of brain DNA methylation across sex, age and Alzheimer's disease points for accelerated epigenetic aging in neurodegeneration

Camilla Pellegrini, Chiara Pirazzini, Claudia Sala…·Maria Giulia Bacalini

This study identifies age-associated DNA methylation changes in Alzheimer's disease, showing accelerated epigenetic aging but no significant sex interaction.

93 citations

humanDNA methylation

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GenomicsAgingPeer-reviewedDec 3, 2020

Age-related DNA methylation changes are sex-specific: a comprehensive assessment

Igor Yusipov, Maria Giulia Bacalini, Alena Kalyakulina…·Claudio Franceschi

The paper assesses sex-specific DNA methylation changes with aging using whole blood datasets, finding 43% of sex-associated probes show age-related methylation changes and higher methylation variability in males.

148 citations

humanDNA methylation

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