Liu Wang

This study identifies T1D-associated SNPs that alter chromatin accessibility at TF binding sites in pancreatic islets, linking genetic risk to cell type-specific regulatory programs.

The paper investigates how developmental DNA damage responses in α- and β-cells contribute to their differential susceptibility to diabetes, showing β-cells have higher DNA damage vulnerability and repair efficiency.

This study identifies FXR and BET signaling cooperation in protecting β cells from diabetes-related dysfunction through protein interaction and functional synergy.

The paper identifies a molecular circuit involving C/EBP and Dlk1 that regulates fate plasticity in AT2 cells during lung development and injury.