Pharmacology & ToxicologybioRxivPreprint
Steroid-based Tide Quencher 1 probes enable real-time mapping of novel non-canonical cholesterol sites on the M1 muscarinic receptor
Nikolai Chetverikov, Eszter Szánti‐Pintér, Jan Jurica…·Eva Kudová
This paper introduces TQ1 probes to map non-canonical cholesterol-binding sites on the M1 muscarinic receptor, showing improved quenching and binding specificity compared to Dabcyl.
DOI 10.64898/2026.03.26.714567