Kenichiro Negishi

This paper develops a computational model of striatal circuits that explains decision-making mechanisms and links them to neuropsychiatric disorders through altered information processing.

This study examines the effects of acute alcohol consumption on decision-making in male and female rats using a novel behavioral task, revealing sex-dependent differences in approach-avoid behavior.

The paper maps the efferent projections of dopaminergic zona incerta neurons in mice, revealing their connectivity to motor-related brain regions and similarities to GABAergic ZI cells.

The paper describes a chronic electrophysiological implant kit for rats that allows precise probe adjustment and modular customization.

This study maps the anatomical connections and activation patterns of the dorsomedial nucleus accumbens (dmACB) and finds reduced dmACB activation correlates with increased opioid seeking after abstinence.

This paper identifies computational strategies for cost-benefit decision-making in humans and rodents, showing their shared use and adaptation based on factors like hunger and sex.

The paper maps reciprocal connections between the cingulate region and the diencephalon in rats, revealing spatial segregation of infralimbic and anterior cingulate area connections.

This study examines the effects of nicotine vapor withdrawal in rats, finding increased plasma cotinine, somatic signs, anxiety-like behavior, and elevated reward thresholds.

The paper identifies a novel hypothalamic neuron population in mice that co-expresses tyrosine hydroxylase and the vesicular GABA transporter, localized primarily in the zona incerta.

The paper validates field methods for preserving lizard brain tissue in remote areas, showing they maintain cytoarchitecture, immunostaining, and imaging quality comparable to lab conditions.