Author

Harry Ischiropoulos

Children's Hospital of PhiladelphiaORCID 0000-0001-8284-5098Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Y. AndreyeviD· 1 shared Angela RollariD· 1 shared Anthony Mastracci· 1 shared Anushka Takhi· 1 shared Ayşe UlusoyiD· 1 shared Bryan Lewis· 1 shared Christine BaaliD· 1 shared Donato A. Di MonteiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alexander Y. AndreyevORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 26, 2026

Antibody treatment targeting nitrated alpha-synuclein counteracts protein spreading pathology

Ayşe Ulusoy, Sarah Wright, Pietro La Vitola…·Donato A. Di Monte

This study shows that targeting nitrated alpha-synuclein with an antibody reduces pathology in Parkinson's disease models and correlates with increased levels in Parkinson's patients.

DOI 10.64898/2026.05.21.726933

mousehuman

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NeuroscienceAdvanced SciencePeer-reviewedJan 18, 2024

Metabolic bypass rescues aberrant S-nitrosylation-induced TCA cycle inhibition and synapse loss in Alzheimer's disease human neurons

Alexander Y. Andreyev, Hongmei Yang, Paschalis‐Thomas Doulias…·Stuart A. Lipton

This study identifies a metabolic block in the TCA cycle in Alzheimer's disease neurons and shows that dimethyl succinate treatment rescues mitochondrial function and synapse loss.

36 citationstop 1%

humanbulk RNA-seq

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